1.简单配置：
需要在原有的web.config中的<system.web>节中添加如下代码
<httpHandlers>
<remove verb="*" path="*.asmx"/>
<add verb="*" path="*.asmx" validate="false" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
<add verb="GET,HEAD" path="ScriptResource.axd" type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" validate="false"/>
</httpHandlers>
如果已经安装了官方的安装包（包括Beta1和CTP），则只需要在以下目录：
C:\Program Files\Microsoft ASP.NET\ASP.NET 2.0 AJAX Extensions\v1.0.61025
找到这两个文件：
Microsoft.Web.Extensions.dll
Microsoft.Web.Preview.dll
并放到网站的/Bin里就行了，之后部署到哪里都能用。
2.如果添加两个DLL AjaxControlToolkit.dll System.Web.Extensions.dll，则配置为：
<httpHandlers>
<remove verb="*" path="*.asmx"/>
<add verb="*" path="*.asmx" validate="false" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
<add verb="GET,HEAD" path="ScriptResource.axd" type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" validate="false"/>
</httpHandlers>
<pages>
<controls>
<add tagPrefix="asp" namespace="System.Web.UI" assembly="System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
<add tagPrefix="web" namespace="WebChart" assembly="WebChart"/>
<add tagPrefix="web" namespace="EeekSoft.Web" assembly="EeekSoft.Web.PopupWin"/>
<add tagPrefix="ajax" namespace="AjaxControlToolkit" assembly="AjaxControlToolkit"/>
</controls>
</pages>
3.让客户端支持PageMethod方法调用Web service
<httpModules>
<add name="ScriptModule" type="System.Web.Handlers.ScriptModule, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
</httpModules>